








Price: $26.75
(as of Mar 14, 2026 19:47:23 UTC – Details)
Product description




Managing cortisol levels and balancing the HPA axis are key for establishing a healthy stress response.*
The hypothalamic-pituitary-adrenal (HPA) axis helps maintain hormonal homeostasis during times of stress. Cortisol is produced by the adrenal cortex and plays an important role in regulating energy metabolism, heart rate, appetite, and immune function. Because of its central role as a key stress hormone, cortisol is often thought of as a bridge between stress and its health impact. Typically, cortisol follows a circadian rhythm, peaking in the morning with a gradual decline throughout the day. However, during times of stress, cortisol is continuously produced and can impact whole-body wellness.
Our best-selling Cortisol Manager contains proprietary blends of Sensoril brand ashwagandha extract and L-theanine and of Magnolia and epimedium extracts, as well as phosphatidylserine, and is designed to:
Balance cortisol levels*
Help reduce stress*
Promote relaxation to support restful sleep*
Integrative Therapeutics’ HPA Adapt combines key adaptogenic herbs to help the body manage both mental and physical stress.*

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Customer Reviews
4.2 out of 5 stars 10,179
4.5 out of 5 stars 1,942
4.6 out of 5 stars 1,342
4.6 out of 5 stars 1,486
4.4 out of 5 stars 2,128
4.5 out of 5 stars 434
Price
$26.75$26.75
$28.50$28.50
$39.50$39.50
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—
$49.25$49.25
Serving Size
2 tablets
2 capsules
4 capsules
2 capsules
1 softgel
1 softgel
Count
30 tablets
30 capsules
120 capsules
60 capsules
60 softgels
60 softgels
Gluten Free
✔
✔
✔
✔
✔
✔
Key Ingredients
Ashwagandha + L-Theanine
Ashwagandha + L-Theanine
Adaptogenic herbal blend
L-Theanine
Lavender oil (WS 1265)
Phosphatidylserine
Product Benefits
Cortisol & stress support
Cortisol & stress support
Adaptogenic stress support
Calm & Relaxation support
Calm & sleep support
Brain & stress support
Is Discontinued By Manufacturer : No
Product Dimensions : 2.22 x 2.22 x 3.95 inches; 1.6 ounces
Item model number : 871791003811
Date First Available : January 2, 2009
Manufacturer : Integrative Therapeutics
ASIN : B002D2JYYG
Best Sellers Rank: #616 in Health & Household (See Top 100 in Health & Household) #2 in Adrenal Extract Nutritional Supplements
Customer Reviews: 4.2 4.2 out of 5 stars (10,179) var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
Best Overall Ashwagandha Supplement*: For stress support, Cortisol Manager has been voted best overall Ashwagandha supplement as seen in Vogue*; it helps support balanced cortisol levels and a healthy response to everyday stress*
Relaxation Support*: Supports relaxation and calm to support restful sleep*
Supports Restful Sleep During Stress*: With ongoing use, this supplement with L-theanine and ashwagandha helps ease occasional sleeplessness disrupted by stress*
Integrative Therapeutics Cortisol Manager: Cortisol Manager does not contain gluten, wheat, or dairy
About Integrative Therapeutics: For over 25 years, patients and clinicians have trusted us for our dedication to quality, potency, and accuracy; transparency around our sourcing and manufacturing processes is part of our quality promise to you



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